Antimicrobial eye drops "Albucidus"
General description of the drug
The tool called "Sulfocetamid" is an international drug with a generic name, which in the Russian pharmaceutical market is known as Albucid eye drops. In the United States of America, this drug is known more as "Bleph-30" and "Bleph-10". In addition, a combined version with prednisone is found abroad and is available in the form of a drug called "Blephamide". In general, the "Albucid" eye drops are an ophthalmologic drug (a derivative of sulfonamides), which has a characteristic antibacterial effect. The instillation of this drug affects only locally, penetration into the human circulatory system is insignificant.
Features pharmacological action
Eye drops "Albucidum" is an antibiotic, the main pharmacological action of which is to block the synthesis of a complex of various amino acids, which are vital for the growth of bacteria.Due to this, first slow down, and then completely stop reproduction and growth of a large number of different pathogens that can cause infection. At the same time, the drug "Sulfocetamid" is most active in relation to streptococci, gonococcal infection, staphylococci, Escherichia coli, chlamydia and other bacteria of gram-negative and gram-positive type.
Pharmacokinetic characteristics of the drug
With regard to the pharmacokinetic characteristics of this antibiotic, a pronounced bacteriostatic concentration of the active substance in the eye fluid (after direct instillation into the conjunctival sac) is observed from thirty to forty minutes to two hours. And this is several times higher than the figures achieved in the case of oral administration of the drug "Sulfacetamid". The manufacturing company also notes that this antimicrobial drug can penetrate the systemic circulation from the conjunctiva and the cornea to a small extent, especially if the connective membrane is inflamed. After some time, the drug (unchanged) is partially removed with urine.
Release form and composition of the drug
This antibiotic is produced in the form of a 20% and 30% clear, colorless or slightly colored solution. Sulfacyl sodium is a major component of these eye drops. For one milliliter of medication, it may be two hundred or three hundred milligrams of a given chemical. As for the auxiliary elements, it is primarily sodium thiosulfate, hydrochloric acid and purified water. Eye drops "Albucid" in plastic bottles with a convenient nozzle-dropper are produced. The volume of one package is usually five or ten milliliters. This antimicrobial drug is dispensed from pharmacies, usually without a prescription. It is recommended to keep an open package with this medicine for no more than one month, after which the characteristic therapeutic effect of the drug diminishes.
Indications for use
Experts recommend using "Albucid" eye drops for the treatment of various eye diseases, including a variety of bacterial infections. For example, this antimicrobial agent is often prescribed to eliminate blepharitis - an inflammatory process that affects the edges of the eyelids,and for the treatment of purulent conjunctivitis - inflammation of the mucous membrane. In addition, these drops very well and quickly help with corneal ulcers, ocular barley and gonorrheal eye diseases. The antibiotic Albucid is also used to eliminate infections triggered by bacteria susceptible to the effects of sulfacyl sodium. Eye drops for children (20% solution) are prescribed, as a rule, in order to prevent blenorrhea - an inflammatory disease of the mucous membrane, accompanied by abundant suppuration, in newborn babies. In this case, the manufacturer emphasizes that the use of the drug in this case is possible only under the constant supervision of a pediatrician.
Features of use and dosing regimen
If we talk about the features of the use of the antimicrobial drug "Albucidus", then doctors recommend digging it in two to three drops five to six times a day. In this case, it is necessary to do this directly in the lower conjunctival sac of the eye. The duration of this drug, depending on the course of a disease, will be from seven to ten days.The specific pattern of use of the drug depends on the severity of those or other symptoms of infection. For example, during an exacerbation of the disease, eye drops are instilled up to six times a day, and as the painful signs decrease, the dosage of the drug gradually decreases. At the same time, adult patients are usually prescribed a 30% solution of the drug, and children - a 20% solution.
List of possible adverse reactions
During the use of antibiotics “Albucid”, a certain number of people may experience a burning sensation, itching, redness of the eyelids, and conjunctival edema. In addition, there is a small risk of tingling and eye irritation. In very rare cases, some patients may also experience photophobia, lacrimation, and temporary visual impairment. Among other things, experts note the risk of allergic reactions to sulfacyl sodium. If any of the listed reactions appear, you should immediately stop using this antimicrobial agent and consult your doctor.It may be necessary to just change the used solution to the droplets with the lowest concentration of sulfacyl-sodium in the composition.
In the case of frequent and prolonged use of antimicrobial drops "Albucid", a certain number of patients may experience conjunctival hyperemia and eye irritation. For this reason, use this tool should be strictly in accordance with the instructions or the prescription of an ophthalmologist. With the appearance of tearing, itching, and any other obvious symptoms of overdose, the concentration of the drug and the frequency of its administration should be reduced.
As for the main precautionary measures that should be followed during the application of "Albucid" drops, first of all it is the inadmissibility of their contact with soft lenses. Otherwise, their transparency may be affected. Before direct use of the drug contact lenses must be removed. You can wear them twenty-five to thirty minutes after instillation. In addition, this antibiotic should be used with great caution to people with hypersensitivity to furosemide, glibenclamide or various diuretic substances,belonging to the pharmacological group of thiazides. And finally, you should always remember that while taking tetracaine, procaine and other local anesthetics, there may be a pronounced weakening of the therapeutic effect.