Antibiotic "Oxacillin": instructions for use
Pharmacodynamic description of the drug
Means "Oxacillin" instructions for use belongs to the group of semi-synthetic antibiotics of penicillin. This medicine is active against such gram-positive and gram-negative microorganisms as staphylococci, streptococci, gonococci, pneumococci, diphtheria, anthrax, meningococci, anaerobic spore-forming strains, and some types of actinomycetes. The basis of the action of the drug "Oxacillin", instructions for use of which are necessarily included, is a violation of the late stages of peptidoglycan synthesis and destruction of bacterial cells, by blocking the process of formation of peptide bonds. If we talk about the pharmacokinetics of this antibiotic, then after intramuscular administration, the highest plasma concentration of the active ingredient is achieved in one to two hours and quickly decreases after four hours.
Features of the release form
The drug "Oxacillin" is a tool that can contain two hundred and fifty, five hundred or one thousand milligrams of oxacillin. At the same time, the company-manufacturer currently releases this medicine in only one form - in the form of a powder, intended for the preparation of solutions for subsequent intramuscular or intravenous administration.
Basic indications for appointment
Assign the drug "Oxacillin" instructions for use recommends mainly for the treatment of pneumonia, angina, bronchitis, cholecystitis, pyelonephritis, pyelitis and cystitis. In addition, this tool is often used for various skin infections and infected wounds. In endocarditis and sepsis, the prescription of the medicine "Oxacillin" is also indicated. These pills are recommended to be taken when kidney infections, burn disease, postpartum infection. In addition, experts actively prescribe this antibiotic in order to prevent the development of postoperative purulent complications after surgical interventions and to prevent inflammation in newborns.
Medical contraindications to use
Take the drug "Oxacillin" instruction does not recommend in case of increased individual sensitivity to penicillin drugs and during breastfeeding. In addition, the list of contraindications includes the period of carrying a child.
List of adverse reactions
The use of the antibiotic "Oxacillin" can provoke the appearance of angioedema, pruritus, diarrhea, vomiting, nausea and urticaria in a number of patients. In addition, bronchospasm, eosinophilia and proteinuria can occur.